This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...

When evolution chases change and never quite catches up, surprising things happen at the level of DNA. A new theory from researchers at the University of Michigan (UM) suggests that genes constantly ...

Emerging research reveals that organisms may never fully catch up to their changing environments, opening new questions about how evolution really unfolds. Credit: Stock New research challenges the ...

For more than half a century, many biologists have leaned on the neutral theory of molecular evolution to explain how DNA and proteins change over time. The idea grew from early work in the 1960s, ...

ANN ARBOR—For a long time, evolutionary biologists have thought that the genetic mutations that drive the evolution of genes and proteins are largely neutral: they're neither good nor bad, but just ...

This repository computes an updated estimate of the fitness effects of mutations of the SARS-CoV-2 genome, based on the work presented in this paper by H.K. Haddox, G. Angehrn, L. Sesta, C.

Our work advances the theory of neutral evolution, paying particular attention to how the holistic fitness landscape structure shapes the process of evolution and gives rise to emergent evolutionary ...

Viruses evolve to survive through adaptive mutations. Through the development of a novel tool for measuring the effects of mutations on evolution, Chun Wu, Ph.D., associate professor in the ...

The bathroom is designed to be a place where you can get refreshed in the morning and relax in the evening. It should feel like a retreat away from the world and the place where you put on a face mask ...