Changes in genes have been linked to the development of different diseases for a while. However, it's not exactly clear what ...

Nucleosomes are barriers to RNA Polymerase II (Pol II) transcribing along gene bodies in eukaryotes. We found that a fragile “tailless nucleosome” could be generated to resolve the Pol II pausing ...

The Phase 1/2 trial is a first-in-human, open-label, multi-national study designed to evaluate the safety, tolerability, and efficacy of TSRA-196 in adults with AATD. Trial participants will receive a ...

For decades, biology textbooks taught that DNA’s story could be told with a single image: two elegant strands twisting in a ...

A newly identified and rare genetic variant slows the growth of mutated blood stem cells and reduces the risk of leukemia.

A newly identified and rare genetic variant slows the growth of mutated blood stem cells, researchers report, and it reduces the risk of leukemia. The ...

Researchers have unveiled a way to flip genes back on without slicing into the genome, a shift that could make CRISPR far ...

A research team reports a promising new strategy: combining two already-approved drugs—silybin, a natural liver-protective ...

Understand the role of reproductive biotech in overcoming biological limits in fertility treatments and enhancing success ...