Cluster randomized trials (CRTs) represent a pivotal design in evaluating public health and clinical interventions where individuals are grouped into clusters (such as schools, hospitals or ...

The randomization of GPs to the intervention or control arm will be conducted externally by the coordinating centre of the study in Greifswald. GPs consenting to participate are reported by the two ...

The Stepped Wedge Cluster Randomized Trial is a research methodology that has been growing in popularity, particularly for pragmatic implementation and dissemination trials. SW-CRTs can have ...

In an open-label, two-period, two-sequence, cross-sectional, cluster-randomized, crossover trial, we assigned hospitals in Ontario, Canada, to use either lactated Ringer’s solution or normal saline ...

Surrogate decision makers for incapacitated, critically ill patients often struggle with decisions related to goals of care. Such decisions cause psychological distress in surrogates and may lead to ...

Introduction Population level screen and treat approach for anaemia reduction could be beneficial but its feasibility and impact remains to be tested.Methods This cluster randomised trial in rural ...