Georgetown University's Lombardi Comprehensive Cancer Center researchers have identified a new way to reprogram T cells, ...

A new JSTAT study shows how to compute the minimum energy cells use to sustain certain metabolic pathways while suppressing ...

Proteins that are no longer needed, defective, or potentially harmful are labeled with a molecular "tag" and dismantled in ...

Living cells pay a hidden energy price not just to run chemical reactions, but to keep them on track and block all the ...

There are “costs of life” that mechanical physics cannot calculate. A clear example is the energy required to keep specific ...

Initial clinical data from the ongoing Phase 1 study of ACR-2316, a potential first- and best-in-class WEE1/PKMYT1 inhibitor, including safety data, dosing regimen, and early clinical activity across ...

By editing thousands of genes in mouse stem cells, the scientists identified a list of over 300 that are crucial for neural differentiation.

The intestinal epithelium undergoes rapid renewal every 3–5 days, a process driven by intestinal stem cells (ISCs) located at ...

Preclinical AML studies showed palbociclib plus venetoclax produced stronger, more durable anti‑leukemia activity than venetoclax alone and may overcome resistance.

Dr Soumojit Pal earned his PhD in Molecular and Cellular Endocrinology from Visva-Bharati University, India, in 2019. He then joined the University of Pittsburgh as a postdoctoral researcher, focusing ...

DuoCAR20.19.22-D95 targets CD19, CD20, and CD22, addressing antigen escape in B-cell malignancies like B-ALL and B-NHL. Early-stage trials show no safety concerns for DuoCAR20.19.22-D95, with ongoing ...