Which genes are required for turning embryonic stem cells into brain cells, and what happens when this process goes wrong? In ...
A large genetic screen has revealed how stem cells transform into brain cells, exposing hundreds of genes that make this ...
The study used large-scale CRISPR gene-editing technology to systematically determine which genes are required as embryonic ...
A sweeping genetic screen reveals how the brain is built and exposes a hidden gene behind a newly discovered childhood brain ...
By editing thousands of genes in mouse stem cells, the scientists identified a list of over 300 that are crucial for neural differentiation.
The brain is often referred to as a "black box" - one that's difficult to peer inside and determine what's happening at any given moment. This is part of the reason why it's difficult to understand ...
Revvity's Dharmacon All-in-one lentiviral platform has expanded to include whole-genome library options for CRISPR knockout (CRISPRko), CRISPR interference (CRISPRi), and CRISPR activation (CRISPRa).
In this interview conducted at SLAS EU 2023 in Brussels, Belgium, we spoke to Ulrike Künzel, Associate Director in the Functional Genomics department at AstraZeneca, about the application of arrayed ...