At the turn of the 20th century, Korbinian Brodmann released one of the most consequential brain maps ever. By studying the humps, grooves, layers, and cells of the cortex—the outermost layer of the ...

Biophysically detailed simulation of the whole mouse cortex neuron by neuron, with sub-cellular resolution—that is, capturing ion flows and fluctuations of membrane voltage within many compartments ...

Optogenetic climbing fiber activation regulates experience-dependent plasticity in the primary somatosensory cortex of mice, suggesting a role of the olivo-cerebellum in instructive signaling across ...

This important study combines optogenetic manipulations and wide-field imaging to show that the retrosplenial cortex controls behavioral responses to whisker deflection in a context-dependent manner.

You might expect that with age comes a natural progression of brain degeneration, but new research shows that this might not be the case for all regions of the brain. A new analysis of mouse and human ...

WASHINGTON — Thanks to a mouse watching clips from “The Matrix,” scientists have created the largest functional map of a brain to date — a diagram of the wiring connecting 84,000 neurons as they fire ...

Researchers have discovered that parts of the human brain age more slowly than previously thought—particularly in the region that processes touch. By using ultra-high-resolution brain scans, they ...

Perhaps our most defining characteristic as a species, the six-layered human cortex, hosts billions of neural connections that bestow Homo sapiens with higher-order thinking. But how does this ...

Myelin loss disrupts the coordination of signals between brain regions, impairing the accurate processing of information, researchers found.